Module 2: Storage, Retrieval and Manipulation of DNA Information (General Themes)
Where is the DNA information stored?
|Various databases (tens of them) store DNA sequences from all of these different sources mentioned in the previous section. We will
look at some of the different databases and the web servers/sites to reach them in the next module
(Module 3). There are databases which store different flavors of DNA information, all the way
from data sets directly off gel reads to sequences which correlate with an unique gene. Although storage of newly generated data is
fairly straight forward (either locally or globally), there is no international effort to standardize the data entry/input methods.
There are a variety of reasons for the lack of such an effort with the leading culprit being the incompatibility of different computing
tools available for the research community generating the DNA sequence information (platforms, software, WWW tools, and etc.). To
alleviate file format compatibility issues, researchers at the San Diego Supercomputer Center
(Biology WorkBench) have developed a web-based tool (using Java) which allows for the analysis
& modeling of protein and nucleic acid sequence data from any input source.